Parkinson's and Medical Marijuana
Researchers targeted a region in the brain, the globus/pallidum, which has the highest amount of CB1-receptors. CB1 receptors respond to Cannabinoids, medicinal compounds found in Medical Marijuana. MRSI results indicate a positive effect of CBD, affecting neurostimulation in the putamen/globus pallidum. This clinical evidence strongly suggests that non-psychoactive forms of Cannabis may influence the onset of Parkinson’s disease and mitigate tremor.”
Parkinson's Disease is a disorder where the motor-nervous system breaks down. This condition is progressive, and begins with slight tremors. Gradually tremors grow in number and severity, accompanied by muscle stiffness, slurred speech, and impaired motion. Parkinson's sufferers can live for many years but eventually the condition greatly compromises quality of life and leads to premature death. The Center for Disease Control classed complications from Parkinson’s disease as the 14th main cause of fatalities in the U.S.
Right now, there is no cure for Parkinson's offered within the public domain. Some experimental drugs, therapies and even brain surgery have shown limited effectiveness in niche applications.
"In fact, Parkinson's has made me a better person. A better husband, father and overall human being." - Michael J. Fox
This is why there is so much excitement about the Cannabinoids found in Medical Marijuana. MRI studies have already found that CBD, a non-psychoactive Cannabinoid, normalized the extrapyramidal motor system. Coupled with clinical studies that show CBD is very safe, Parkinson's sufferers can legally medicate in California - right now.
- Stiff muscles
- Impaired movement
- Decline in Writing and Speech
- Genetic susceptibility to man-made environmental toxins
- Protein Metabolism defect - Rogue peptides clog nerve tissue
- Defective chromosomes, others speculated
- Carbidopa / levodopa
Sinemet Side Effects: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; chest pain; confusion; dark urine; eye pain; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; new or increased involuntary movements; new or worsening mental, mood, or behavior changes (eg, depression, anxiety, restlessness, irritability); severe or persistent dizziness or headache; shortness of breath; stomach pain; suicidal thoughts or actions; unusual bruising or bleeding; unusual or painful movements or spasms of the face, eyelids, mouth, tongue, arms, hands, or legs; unusual tiredness or weakness; vision changes; vomiting blood or vomit that looks like coffee grounds; yellowing of the skin or eyes. - Source: www.drugs.com
Doctor's Testimonials: How to Medical Marijuana can Help in Parkinson's
"Our MRSI results support a positive effect of CBD on the putamen/globus pallidum region in cannabis use. Therefore, it may be promising to test a possible influence of the non psychotropic CBD in the onset of Parkinson’s disease.”
"CBD at doses ranging from 150 mg in the first week to 400 mg in the fourth and last week of treatment reported significant improvements in psychosis and general symptoms of PD."
Effects of cannabidiol in the treatment of patients with Parkinson’s disease: "The researchers hypothesized that these improvements may have been due to cannabidiol anxiolytic, antidepressant, antipsychotic,and sedative properties."
"There was also significant improvement of sleep and pain scores. No significant adverse effects of the drug were observed. The study suggests that cannabis might have a place in the therapeutic armamentarium of PD. Larger, controlled studies are needed to verify the results."
- Source: Various publications PubMed.
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FURTHER READING - HOW MEDICAL MARIJUANA HELPS WITH PARKINSON'S DISEASE
"Joe Frazier got hit more than me - and he doesn't have Parkinson's." - Muhammad Ali